Tongue cancer remains a threat to the world community. Even patients with tongue cancer continues to increase every year. One cause of this disease because of smoking. Besides containing allicin as an anti-inflammatory and anti-cholesterol, garlic are known to prevent the growth of cancer cells because of its ability as an agent for anti-proliferation (cell growth) and indoktor apotosis (programmed cell death) in cancer cells.
From the test results on the tongue cancer cells Sprague Dawley rats, known ektstrak ethanolic antipolifersi garlic has an effect on cancer cells by triggering termination tongue at the stage of the cell cycle G2 / M. "There was induction of apoptosis in rat tongue cancer cells, which means the ethanolic extract of garlic may inhibit the growth of cancer cells through induction of apoptosis.
Today, garlic is widely used in preventing the incidence of heart disease, including atherosclerosis, hypercholesterolemia and hypertension. Garlic is also associated with anti-cancer, anti-fungal and anti-bacterial. In addition, the traditional garlic also used in treating diabetes type I and II in Asia, the Middle East and Europe. The active component in garlic that plays a role for medical purposes is allicin (diallyl disulphide oxide) and APDS (allyl propyl disulfide), flavonoids and so on. Garlic is believed to stimulate the pancreas to increase insulin production.
One of the plants that have medicinal properties of garlic (Allium sativumL.). The earliest information about the medicinal properties of plants started around the year 3000 BC by the Chinese, and the tribes of the rover (nomad) Central Asia who used it to ward off evil spirits and maintain health (Aaron, 1996). Part of the garlic plant is the most nutritious tuber. Besides commonly used as a spice in cooking, garlic bulbs also used to normalize blood pressure and prevent cancer.
Some literature suggests the negative effects of consumption of garlic, but most do not have enough evidence, only a preliminary study, case studies or epidemiological studies. Alleged garlic diet associated with oral cancer is not true, since garlic is anti-cancer. The cancer is a result of brushing to remove the pungent smell wrong. One scientific study with sufficient evidence of the negative effects of garlic is the study of hepatocytes in mice. Research shows that garlic extract is valuable for detoxification and antioxidants at levels of 1 mM, 5 mM, but at levels significantly can reduce cell viability, cell morphology change, and lower activity.
Garlic bulbs safe for human consumption at the normal dose, ie, less than three bulbs per day. At these doses, the toxicity and side effects of the consumption of garlic bulbs yet. Even for pregnant and lactating women, garlic bulbs showed no negative effects. In the rare cases, garlic may cause allergies. Garlic is also no negative effect on the secretion of digestive enzymes. The positive effects of garlic consumption are much higher than its negative effects. Recent studies show garlic is a panacea to improve the vitality of the body like ginseng.
Garlic bulbs can be used traditionally to treat high blood pressure, respiratory problems, headaches, hemorrhoids, constipation, bruising or slice, worms, insomnia, cholesterol, colds, urinary tract disorders, and others. Meanwhile, based on scientific research that has been done, garlic bulbs can be used as an anti-diabetic, anti-hypertensive, anti-cholesterol, anti-atherosclerosis, anti-oxidant, anti-cell aggregation of platelets, hyper fibrinolysis, anti-virus, anti-microbial and anti-cancer. The main bioactive compounds garlic is alliin, allisin, ajoene, group allyl sulfide, and allyl cysteine. Side effects and toxicity of garlic is not found so, safe for consumption.
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